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Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 on the active metabolite N-desmethyldiazepam, which is hydroxylated by CYP3A4 to the Energetic metabolite temazepam.Disclaimer: This informative article is for data only and should not be used for the analysis or therapy of health care ailments. Egton Health-related Information Techniques Lim